John H. MARKS, M.D.
Curriculum Vitae

Marks Colorectal Surgical Associates
Lankenau Hospital
Jefferson Health System

PATIENT OFFICE:
Marks Colorectal Surgical Associates
Medical Office Building West
Suite 330
100 Lancaster Avenue
Wynnewood, Pennsylvania 19096
Telephone: (610) 645-9093
FAX: (610) 645-9476

Marks Colorectal Surgical Associates
227 North Broad Street
Suite 100
Philadelphia, Pennsylvania 19107
Telephone: (215)-923-5010
FAX: (610)-645-9476

EDUCATION:

Yale University, New Haven, CT, BS, 1985
Jefferson Medical College, Phila., PA, MD,1989

POST-GRADUATE TRAINING:

General Surgery Resident
Thomas Jefferson University Hospital 1989-1994

Colorectal Surgery Fellowship
Thomas Jefferson University Hospital July 1994-July 1995

Advanced Laparoscopy Fellowship
University of Nice, Hospital St. Roch July 1995-January 1996

BOARD CERTIFICATION:
Diplomate, American Board of General Surgery, 1996
Diplomate, American Board of Colon and Rectal Surgery, 1997

LICENSURE: Pennsylvania

CURRENT PROFESSIONAL POSITIONS:

Co-Director, Marks Colorectal Surgical Associates, Lankenau Hospital, Wynnewood, Pennsylvania, November 1998 to Present

Senior Investigator, Lankenau Institute for Medical Research (LIMR), Lankenau Hospital, Wynnewood, Pennsylvania, July 1999 to Present

Assistant Professor of Surgery, Hahnemann University, Philadelphia, Pennsylvania, January 1996 to Present

Secretary, International Network of Comprehensive Rectal Cancer Centers (INCRCC), Lankenau Hospital, Wynnewood, Pennsylvania, May 1997 to Present

Committee Member, Technologies Committee, American Society of Colon and Rectal Surgeons, June 1999 to Present

Committee Member, Standards of Practice Committee, Society of American Gastrointestinal Endoscopic Surgeons (SAGES), January 1998 to Present

Committee Member, Legislative Review Committee, Society of American Gastrointestinal Endoscopic Surgeons (SAGES), January 1998 to Present

HOSPITAL AFFILIATIONS:

Lankenau Hospital, Wynnewood, Pennsylvania
Bryn Mawr Hospital, Bryn Mawr, Pennsylvania
Paoli Hospital, Paoli, Pennsylvania
Hahnemann University Hospital, Philadelphia, Pennsylvania

RESEARCH PROJECTS:

Principal Investigator

1. Randomized Trial of Open Colectomies Versus Hand-Assisted Laparoscopic Colectomies with Intromit. Sponsored by MedTech Limited, Dublin, Ireland.

2. (on-going)

3. Phase III Prospective Randomized Trial Comparing Laparoscopic-Assisted Colectomy Versus Open Colectomy for Colon Cancer, National Surgical Adjuvant Breast and Bowel Project/National Cancer Institute. (on-going)

4. A Clinical Trial to Evaluate the Worth of Preoperative Multimodality Therapy (5FU and RTX) in Patients with Operable Carcinoma of the Rectum. (on-going)

5. Detection of Cancer Cells in Peripheral Blood of Patients with Colorectal Cancer (Immunicon Corporation). (on-going)

6. Prospective Randomized Trial on the Treatment of Rectal Cancer in T1 G2-3 and T2 G1-3 N0 M0 Patients: Preoperative Radiochemotherapy and Local Excision Versus Anterior Resection or Abdominoperineal Resection. (on-going)

Co-Investigator

1. Evaluation of the Efficacy, the Safety and the Tolerability of Enterokinetic Given Subcutaneously in Patients Undergoing Elective Partial Colectomies. Funded by Janssen Pharmaceutica Research Foundation, 1997 to 1998.

MEDICAL SOCIETY MEMBERSHIPS:

American College of Surgeons, 1994 to Present
American Medical Association, 1996 to Present
American Society of Colon and Rectal Surgeons (Fellow), 1995 to Present
Association for Academic Surgery, 1996 to Present
Pennsylvania Medical Society, 1996 to Present
Pennsylvania Society of Colon and Rectal Surgeons, 1996 to Present
Philadelphia County Medical Society, 1996 to Present
Society of American Gastrointestinal Endoscopic Surgeons, 1996 to Present
Society of Laparoendoscopic Surgeons, 1994 to Present
Society for Surgery of the Alimentary Tract, 1996 to Present

HONORS AND AWARDS:

Bacon Foundation Award for Excellence in Research and Presentation. Presented by the American Society of Colon and Rectal Surgeons, May 3, 1999, for "Detection of Colorectal Cancer Cells in Peripheral Blood Using Ferrofluids."

Jefferson Laparoscopic Surgery Award. Presented by the Thomas Jefferson University School of Medicine, 1994.

Jefferson Award for Excellence in Research. Presented by the Thomas Jefferson University School of Medicine, 1993.

Lifetime Member, National Registry of Who's Who, 1999.

SPECIAL ACHIEVEMENTS:

Faculty Member, Society of American Gastrointestinal Endoscopic Surgeons (SAGES) Meeting of the Millennium, Atlanta, Georgia, March 29 to April 1, 2000.

Invited as one of a four-person group representing the International Network of Comprehensive Rectal Cancer Centers (INCRCC) at a special meeting of the National Surgical Adjuvant Breast and Bowel Project (NSABP). NSABP Headquarters, March 6, 2000, Pittsburgh, Pennsylvania. (The INCRCC provided the foundation for a new national rectal cancer trial.)

Selected as one of two expert colorectal surgeons in the United States to present informational seminar on Transanal Endoscopic Microsurgery (TEM). Sponsored by Richard Wolf Medical Instruments Corporation, Society of American Gastrointestinal Endoscopic Surgeons (SAGES) Meeting of the Millennium, Atlanta, Georgia, March 30 and 31, 2000.

MEDIA ACTIVITIES:

"Colorectal Disease." Radio interview for Medical Frontiers hosted by Joel Posner, M.D., August 14, 1996.

"Laparoscopic Surgery." Radio interview for Medical Frontiers hosted by Joel Posner, M.D., November 20, 1996.

Featured in "Simple Blood Test May Detect Colon Cancer." The Main Line Times, Thursday, May 27, 1999, p. 34.

"Colon and Rectal Cancer Screening Techniques and New Frontiers in Laparoscopic Surgery." Interview with Dorie Lenz, Host of Community Close-Up, WPHL-TV/WB 17, Philadelphia, Pennsylvania, Airing June 8, 10, 12, 1999.

"Blood Test to Detect Colon Cancer." Interview for WPVI-TV 6 News, Philadelphia, Pennsylvania, July 22, 1999.

Featured in "Ferrofluids Help Detect Cancer Cells in Peripheral Blood Flow." General Surgery News, September 1999, p. 16.

"Colon and Rectal Cancer Detection and Treatment" by John Marks, M.D. The Best of Times: A Special Edition of Courier News Weekly, September/October 1999, pp. 26-27.

Featured in "Colo-Rectal Cancer." Reading Eagle/Reading Times, December 21, 1999, Section C, pp. 1 & 4.

"Latest Treatment Advances in Colorectal Disease for Women." Interview with WPPX 61 PAX-TV, Philadelphia, Pennsylvania, March 20, 2000.

PUBLICATIONS:

Marks J, Marks G, Rifkin M, Mohiuddin M. Evaluation of Endorectal Sonography, Computerized Tomography, and Digital Examination in the Prospective Staging of Rectal Cancer. Surg Endos, 1988; 2(2):122.

Marks G, Marks J. Anoscopy and Flexible Fiberoptic Sigmoidoscopy: Evaluation of the Distal 50 cm of Colorectum in Endoscopic Surgery. F.L. Green and J.L. Ponsky, eds. W.B. Saunders, Philadelphia, PA, 1994.

Marks G, Marks J. Dukes C2 Colon Cancer: What Is Appropriate Follow Up? Seminars in Oncology, 1995; 22(3):I-IX.

Marks G, Marks J, Mohiuddin M. Preoperative Radiation and Resection With Coloanal Anastomosis for Low Lying Rectal Cancer in Surgery for Gastrointestinal Cancer: A Multidisciplinary Approach. H. Wanebo, ed. J.B. Lippincott, Philadelphia, PA, 1996.

Marks G, Bannon JP, Marks J. Transanal-Abdominal Transanal-Radical Proctosigmoidectomy With Coloanal Anastomosis for Distal Rectal Cancer in Mastery of Surgery, 3rd edition. Lloyd Nyhus, Robert Baker, Josef Fischer, eds. Little, Brown and Company, Boston, MA, 1996.

Marks J, Mouiel J, Katkhouda N, Guggenheim J, Fabiani P. Laparoscopic Liver Surgery: A Report of 28 Cases. Surg Endos, 1997:11(1).

Barbot DJ, Marks J, Feld RI, Liu Ji-B, Rosato FE. Improved Staging of Liver Tumors Using Laparoscopic Intraoperative Ultrasound. J Surg Onc, January 1997; 64(1):63-67.

Marks J. Techniques in Coloproctology. Colorectal Cancer Session at the American Society of Colorectal Surgery, 1997.

Mohiuddin M, Regine W, Marks G, Marks J. High-Dose Preoperative Radiation and the Challenge of Sphincter Preservation Surgery for Cancer of the Distal 2 CM of the Rectum. Int J Rad Onc Biol Phys, 1998; 40(3):569-574.

Marks G, Marks J, Mohiuddin M, Brady L. Radical Sphincter Preservation Surgery With Coloanal Anastomosis Following High-Dose External Irradiation for the Very Low Lying Rectal Cancer in Recent Results in Cancer Research, Vol. 146. Peter Schlag, ed. Springer, Berlin, Germany, 1998.

PRESENTATIONS:

Evaluation of Endorectal Sonography, computerized Tomography, and Digital Examination in the Prospective Staging of Rectal Cancer. J. Marks, G. Marks, M. Rifkin, M. Mohiuddin. Presented at The First International Congress of Surgical Endoscopy, Ultrasound and Interventional Techniques, Berlin, West Germany, July 1, 1988.

Endorectal Sonography. G. Marks, L. Masoni, and J. Marks. Presented at Gastrointestinal Endoscopy: New Horizons in Diagnosis and Therapy, sponsored by The University of South Florida: Lake Buena Vista, FL, December 7-10, 1988.

Laparoscopic Cholecystectomy Results. D. Rose, A. Coletta, J. Kairys, and J. Marks. Presented at the Conjoint Meeting of the Philadelphia Academy of Surgery and The New York Surgical Society, Philadelphia, PA, March 1991.

Sphincter Preservation Following High-Dose Radiation of Fixed Rectal Cancer. J. Marks, G. Marks, M. Mohiuddin, J. Rakinic, and L. Masoni. Presented at International Surgical Week, Stockholm, Sweden, August 25-31, 1991.

Full Thickness Local Excision After High-Dose Radiation: A New Option for Select Distal Rectal Cancers. J. Marks, J. Bannon, G. Marks, M. Mohiuddin, and J. Rakinic. Presented at Resident Research Day, Thomas Jefferson University Hospital, Philadelphia, PA, June 1993.

Coloanal Anastomosis with Radical Proctosigmoidectomy Following High-Dose External Radiation for Distal Rectal Cancer. J. Marks, J. Bannon, G. Marks, M. Mohiuddin, and J. Nong-Zhou. Presented at Resident Research Day, Thomas Jefferson University Hospital, Philadelphia, PA, June 1994.

Full Thickness Local Excision After High-Dose Radiation: A New Option for Select Distal Rectal Cancers. J. Marks, J. Bannon, G. Marks, and M. Mohiuddin. Presented at the Tianjian Surgical Society, Tianjian, People's Republic of China, October 28, 1994.

Full Thickness Local Excision After High-Dose Radiation: A New Option for Select Distal Rectal Cancers. J. Marks, J. Bannon, G. Marks, and M. Mohiuddin. Presented at Grand Rounds, Jiangsu Cancer Hospital and Institute, Nanjing, People's Republic of China, November 1, 1994.

Full Thickness Local Excision After High-Dose Radiation: A New Option for Select Distal Rectal Cancers. J. Marks, J. Bannon, G. Marks, and M. Mohiuddin. Presented at the Nanjing Medical Society, Nanjing, People's Republic of China, November 1, 1994.

Laparoscopic Approaches to the Liver. J. Marks and J. Mouiel. Presented at Grand Rounds, La Sapienza, University of Rome, Rome, Italy, October 1995.

Local Modalities for Treatment of Rectal Cancer. J. Marks and G. Marks. Presented at Grand Rounds, Hospital St. Roch, Universite de Nice, Nice, France, November 1995.

Laparoscopic Hepatic Surgery: Indications, Techniques, and Results. J. Marks and J. Mouiel. Presented at the 46 Annual Meeting of the American College of Surgeons, Puerto Rico Chapter, San Juan, Puerto Rico, February 15, 1996.

Laparoscopic Liver Surgery: A Report on 28 Patients. J. Marks, J. Mouiel, J. Guggenheim, and P. Fabiani. Society of American Gastrointestinal Endoscopic Surgeons, 1996 Scientific Session of the 5th World Congress of Endoscopic Surgery, Philadelphia, PA, March 14, 1996.

A Ten-Year Experience with High-Dose Preoperative External Radiation Therapy and Full Thickness Local Excision for Select Distal Rectal Cancer. J. Marks, G. Marks, L. Masoni, and M. Mohiuddin. Society of Surgical Oncology, 49th Annual Cancer Symposium, Atlanta, GA, March 23, 1996.

Rectal Cancer: Alternatives to Miles Resection. J. Marks and J. Bannon. American College of Surgeons, Eastern Pennsylvania Chapter, Scranton, PA, October 25, 1996.

Laparoscopic Hepatic Surgery. J. Marks and J. Mouiel. Philadelphia Academy of Surgery, Philadelphia, PA, December 2, 1996.

Vaginal Wall Preservation with Curative Sphincter Preservation Surgery for Rectal Cancer Following High-Dose External Irradiation. J. Marks, G. Marks, and M. Mohiuddin. Presentation at Annual Meeting of the American Radium Society, New York, New York, May 4, 1997.

The Prognostic Implications of the Post-Radiated Stage pT0 Rectal Cancer. J. Bannon, J. Marks, G. Marks. Poster presentation at Annual Meeting of The American Society of Colon and Rectal Surgeons, Philadelphia, PA, June 23, 1997.

Vaginal Wall Preservation with Curative Sphincter Preservation Surgery for Rectal Cancer Following High-Dose External Irradiation. J. Marks. Presentation at The Fourth International Conference on Gastrointestinal Oncology, Pentagon City, Virginia, September 13, 1997.

A Ten-Year Experience with High-Dose Preoperative External Radiation Therapy and Full Thickness Local Excision for Select Distal Cancer. J. Marks. Presentation at The Fourth International Conference on Gastrointestinal Oncology, Pentagon City, Virginia, September 13, 1997.

The Prognostic Implications of the Post-Radiated Stage pT0 Rectal Cancer. J. Marks. Poster presentation at the 2nd Annual Research Conference and Retreat, Valley Forge, PA, October 9, 1997.

Full Thickness Local Excision for Select Distal Rectal Cancer. J. Marks. Presentation at the Conjoint Meeting of the Philadelphia Academy of Surgery and the New York Surgical Society, Philadelphia, PA, March 18, 1998.

Local Control of Rectal Cancer and Its Impact on Distant Metastases in Patients Treated with High-Dose Preoperative External Irradiation and Sphincter Preservation Surgery. J. Marks, G. Marks, and M. Mohiuddin. Presentation at the 80th Annual Meeting of the American Radium Society, Monte Carlo, Monaco, May 6, 1998.

Rectal Cancer: The Impact of High-Dose Preoperative Irradiation on Distal Surgical Markings. J. Marks. Presentation at The Society for Surgery of the Alimentary Tract, Digestive Disease Week, New Orleans, LA, May 18, 1998.

Minimally Invasive Colorectal Surgery. J. Marks. Presentation at the Wound Ostomy and Continence Nurses Association Conference, Salt Lake City, Utah, June 14-15, 1998.

An Analysis of Minimal Distal Margins in a Program of Preoperative Irradiation and Sphincter Preservation Surgery for Low Rectal Cancers. J. Marks, G. Marks, and M. Mohiuddin. Presentation at the III International Symposium of Sphincter Saving Surgery of Rectal Cancer, Milan, Italy, December 10-12, 1998.

Local Management of Rectal Cancer. J. Marks. Presentation at the 49th Annual Meeting of the American College of Surgeons, Puerto Rico Chapter, San Juan, Puerto Rico, February 10, 1999.

Rectal Cancer: The Impact of High-Dose Preoperative Irradiation and Sphincter Preservation Surgery on Distal Surgical Margins. J. Marks, J. Cotter, G. Marks, and M. Mohiuddin. Poster presentation at Lankenau Medical Research Center Poster Day, Lankenau Hospital, Wynnewood, PA, February 16, 1999.

Detection of Colorectal Cancer Cells in Peripheral Blood Using Ferrofluids. J. Marks, A. Weiss, L. Terstappen. Presentation at the 100th Anniversary and Tripartite Meeting of the American Society of Colon and Rectal Surgeons, Washington, DC, May 3, 1999.

Shaking the Tree of Tradition: Advances in Colon and Rectal Surgery - The Jefferson Contribution. J. Marks. Presentation at the 50th Reunion, Jefferson Medical College, Philadelphia, PA, June 5, 1999.

New Surgical and Diagnostic Options. J. Marks. Invited Speaker, "Frankly Speaking About Colorectal Cancer: A Symposium for People Living with Colorectal Cancer, Their Families, Health Professionals, and Interested Others," Wellness Community of Philadelphia, Philadelphia, PA, November 6, 1999.

The Marks-Mohiuddin Experience of High-Dose Preoperative Radiation and Sphincter Saving Surgery. J. Marks. Presentation at the Annual Meeting of the Northeast Society of Colon and Rectal Surgeons, Palm Beach, Florida, November 9, 1999.

New Hope and Promise in Colorectal Diseases of Women. J. Marks. Invited Speaker, Women's Health Source at Lankenau Hospital, Wynnewood, PA, November 10, 1999.

Colorectal Cancer. J. Marks. Invited Speaker, Owls Group at Lankenau Hospital, Wynnewood, PA, November 17, 1999.

Detection of Colorectal Cancer Cells in Peripheral Blood Using Ferrofluids. J. Marks, A. Weiss, L. Terstappen. Poster Presentation, Lankenau Institute for Medical Research Poster Day, Wynnewood, PA, March 8, 2000.

The Prognostic Implications of the Post-Radiated Stage pT0 Rectal Cancer. J. Marks, J. Bannon, G. Marks. Poster Presentation, Lankenau Institute for Medical Research Poster, Wynnewood, PA, March 8, 2000.

Sphincter Preservation Options Utilizing High-Dose Preoperative Irradiation for Distal Rectal Cancer in the Elderly. J. Marks, C. Bartos, G. Marks, M. Mohiuddin. Poster Presentation, Society of Surgical Oncology 53rd Annual Cancer Symposium, New Orleans, Louisiana, March 16 to 19, 2000.

(04/17/00)